How safe is ARA290
Yes, ARA-290 is still an experimental peptide, but so far, there is no evidence demonstrating unwanted side effects or toxicity.
A 2012 study published in Molecular Medicine concluded that
“the acceptable safety profile noted for ARA 290 in this patient group with sarcoidosis, as well as an apparent reduction of symptoms of SFN, encourages a larger study of the potential effects of ARA 290 for this unmet medical need.”
The FDA has not yet approved ARA-90 but they do recognize it as an orphan drug for the treatment of sarcoidosis-induced neuropathic pain.
A 2014 review of two separate Phase II clinical studies showed that ARA 290 treatment consistently improved neuropathic pain symptoms in sarcoidosis patients.
How does ARA290 work? ARA-290 was developed after Ariam Pharmaceuticals’ discovered the Innate Repair Receptor (IRR). EPO binds to the IRR and activates several anti-inflammatory pathways, but if you don’t have enough EPO to activate the IRR, then, well, your up Schitt’s Creek. Researchers haven’t found a way to use human EPO to successfully treat inflammation or other forms of neuropathic pain, so they created a peptide that would target the IRR. ARA 290 activates the β-common-receptor. The β-common-receptor and the EPO receptor form an innate repair receptor. The local anti-inflammatory response is then triggered, reduces the pain, and promotes tissue repair. ARA-290 provides the therapeutic effects of EPO without the over-production of red blood cells or other unwanted side effects.
How it works
According to research, ARA-290 is very helpful for neuropathic pain. It can help decrease symptoms like hypersensitivity to pain for no apparent reason.
According to the trials, ARA290 can be used for 30 days. Pain can become near non-existent within 6 months due to the decreased reactivity of nerve cells.
The ARA290 peptide dosage
This is where your personal situation comes in. You and your provider may need to take some time experimenting to figure out what works best for you. 0.33 mL daily subcutaneous injection of a 4 mg/mL ARA-290 solution (i.e. 1.32 mg per day) for a total of 30 days is recommended.
Some people suffering from more severe levels of pain take as much as 4 mg per day.
What happens after 30 days? The expectation is that you will experience lowered inflammation and reduced pain within six months. Benefits should start kicking in around 2-3 weeks into your daily injection protocol.
Get the ARA-290 Peptide for Your Neuropathy Now
If you want to use ARA290 peptides for neuropathy, you’ll need to do your due diligence. ARA-290 is a new and much lesser-known compound than many others, so it isn’t easy to find. There are few vendors in existence who even know about ARA-290, so it’s extremely difficult to find. Exercise extreme caution when choosing who to purchase this peptide from, unless, of course, you choose us. We’ve done your due diligence for you by thoroughly vetting and selecting the best quality product that you can buy.
We make it easy to kick neuropathy’s butt
- Book a Peptide consult with us!
- Only requires one lab
- Have a 20-minute phone consultation
- Medication is delivered to your door within 48-72 hours
- Refills are available on the online store for the following 12 months
Resources
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2012 study
An orphan drug
2014 review
Innate Repair Receptor (IRR)
Activates several anti-inflammatory pathways
Other unwanted side effects
